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Intracellular allosteric antagonism of the CCR9 receptor

Intracellular allosteric antagonism of the CCR9 receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1847882459

Intracellular allosteric antagonism of the CCR9 receptor

About this item

Full title

Intracellular allosteric antagonism of the CCR9 receptor

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2016-12, Vol.540 (7633), p.462-465

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The crystal structure of the CCR9 chemokine receptor in complex with vercirnon at 2.8 Å resolution.
Small-molecule chemokine receptor antagonists
Chemokine receptors are a family of G-protein-coupled receptors that regulate the migration of immune cells; their function has been implicated in a range of diseases. Two groups reporting in this i...

Alternative Titles

Full title

Intracellular allosteric antagonism of the CCR9 receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1847882459

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1847882459

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature20606

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