Maintaining cell identity: PRC2-mediated regulation of transcription and cancer
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In this Opinion article, the authors propose that the function of Polycomb repressive complex 2 (PRC2) in maintaining, rather than specifying, transcriptional repression can explain its seemingly contradictory roles in cancer.
Enhancer of zeste homologue 2 (EZH2), the catalytic subunit of Polycomb repressive complex 2 (PRC2), has attracted broad...
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Maintaining cell identity: PRC2-mediated regulation of transcription and cancer
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TN_cdi_proquest_miscellaneous_1850786357
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1850786357
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc.2016.83
