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Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the...

Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1850792844

Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the receptor to its cognate G proteins

About this item

Full title

Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the receptor to its cognate G proteins

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Naunyn-Schmiedeberg's archives of pharmacology, 2016-12, Vol.389 (12), p.1289-1300

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

There are some indications that biased μ-opioid ligands may diversely affect μ-opioid receptor (MOR) properties. Here, we used confocal fluorescence recovery after photobleaching (FRAP) to study the regulation by different MOR agonists of receptor movement within the plasma membrane of HEK293 cells stably expressing a functional yellow fluorescent...

Alternative Titles

Full title

Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the receptor to its cognate G proteins

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1850792844

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1850792844

Other Identifiers

ISSN

0028-1298

E-ISSN

1432-1912

DOI

10.1007/s00210-016-1293-8

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