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In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant C...

In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant C...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1852684237

In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633

About this item

Full title

In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633

Publisher

New York: Nature Publishing Group US

Journal title

Pediatric research, 2017-02, Vol.81 (2), p.369-375

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Background:
CHF5633 is a new generation synthetic surfactant containing both SP-B and SP-C analogues developed for the treatment of respiratory distress syndrome. Here, the optimal dose and its performance in comparison to the animal-derived surfactant poractant alfa were investigated.
Methods:
In vitro
surfactant activity was determine...

Alternative Titles

Full title

In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1852684237

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1852684237

Other Identifiers

ISSN

0031-3998

E-ISSN

1530-0447

DOI

10.1038/pr.2016.231

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