Solid lipid nanoparticles as vesicles for oral delivery of olmesartan medoxomil: formulation, optimi...
Solid lipid nanoparticles as vesicles for oral delivery of olmesartan medoxomil: formulation, optimization and in vivo evaluation
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Publisher
England: Taylor & Francis
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Language
English
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Publisher
England: Taylor & Francis
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Scope and Contents
Contents
Objective: Olmesartan medoxomil (OLM) is an antihypertensive drug with low oral bioavailability (28%) resulting from poor aqueous solubility, presystemic metabolism and P-glycoprotein mediated efflux. The present investigation studies the role of lipid nanocarriers in enhancing the OLM bioavailability through oral delivery.
Materials and methods...
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Full title
Solid lipid nanoparticles as vesicles for oral delivery of olmesartan medoxomil: formulation, optimization and in vivo evaluation
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TN_cdi_proquest_miscellaneous_1852779712
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1852779712
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ISSN
0363-9045
E-ISSN
1520-5762
DOI
10.1080/03639045.2016.1275666
