The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its...
The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The signaling adaptor TRAF1 is involved in TNFR-induced survival. Watts and colleagues demonstrate that TRAF1 also negatively regulates NF-κB activation by interfering with linear ubiquitination of the signaling subunit NEMO.
TRAF1 is a signaling adaptor known for its role in tumor necrosis factor receptor-induced cell survival. Here we show tha...
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The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease
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TN_cdi_proquest_miscellaneous_1859468494
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859468494
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1529-2908
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1529-2916
DOI
10.1038/ni.3618