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The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its...

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859468494

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease

About this item

Full title

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2017-01, Vol.18 (1), p.26-35

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The signaling adaptor TRAF1 is involved in TNFR-induced survival. Watts and colleagues demonstrate that TRAF1 also negatively regulates NF-κB activation by interfering with linear ubiquitination of the signaling subunit NEMO.
TRAF1 is a signaling adaptor known for its role in tumor necrosis factor receptor-induced cell survival. Here we show tha...

Alternative Titles

Full title

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1859468494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859468494

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3618

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