Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an internati...
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial
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Author / Creator
Swisher, Elizabeth M, Dr Prof , Lin, Kevin K, PhD , Oza, Amit M, Prof , Scott, Clare L, PhD , Giordano, Heidi, MA , Sun, James, PhD , Konecny, Gottfried E, MD , Coleman, Robert L, Prof , Tinker, Anna V, MD , O'Malley, David M, MD , Kristeleit, Rebecca S, MD , Ma, Ling, MD , Bell-McGuinn, Katherine M, MD , Brenton, James D, Prof , Cragun, Janiel M, MD , Oaknin, Ana, MD , Ray-Coquard, Isabelle, Prof , Harrell, Maria I, PhD , Mann, Elaina, MS , Kaufmann, Scott H, Prof , Floquet, Anne, MD , Leary, Alexandra, MD , Harding, Thomas C, PhD , Goble, Sandra, MS , Maloney, Lara, BA , Isaacson, Jeff, PhD , Allen, Andrew R, MD , Rolfe, Lindsey, MBChB , Yelensky, Roman, PhD , Raponi, Mitch, PhD and McNeish, Iain A, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background Poly(ADP-ribose) polymerase (PARP) inhibitors have activity in ovarian carcinomas with homologous recombination deficiency. Along with BRCA1 and BRCA2 (BRCA) mutations genomic loss of heterozygosity (LOH) might also represent homologous recombination deficiency. In ARIEL2, we assessed the ability of tumour genomic LOH, quantified...
Alternative Titles
Full title
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Lin, Kevin K, PhD
Oza, Amit M, Prof
Scott, Clare L, PhD
Giordano, Heidi, MA
Sun, James, PhD
Konecny, Gottfried E, MD
Coleman, Robert L, Prof
Tinker, Anna V, MD
O'Malley, David M, MD
Kristeleit, Rebecca S, MD
Ma, Ling, MD
Bell-McGuinn, Katherine M, MD
Brenton, James D, Prof
Cragun, Janiel M, MD
Oaknin, Ana, MD
Ray-Coquard, Isabelle, Prof
Harrell, Maria I, PhD
Mann, Elaina, MS
Kaufmann, Scott H, Prof
Floquet, Anne, MD
Leary, Alexandra, MD
Harding, Thomas C, PhD
Goble, Sandra, MS
Maloney, Lara, BA
Isaacson, Jeff, PhD
Allen, Andrew R, MD
Rolfe, Lindsey, MBChB
Yelensky, Roman, PhD
Raponi, Mitch, PhD
McNeish, Iain A, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1859489887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859489887
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(16)30559-9