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Ca super(2+) signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

Ca super(2+) signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859501836

Ca super(2+) signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

About this item

Full title

Ca super(2+) signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

Journal title

Cellular and molecular life sciences : CMLS, 2017-01, Vol.74 (1), p.173-181

Language

English

Formats

More information

Scope and Contents

Contents

Activated receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like (MLKL) are essential components of the necroptotic pathway. Phosphorylated MLKL (pMLKL) is thought to induce membrane leakage, leading to cell swelling and disintegration of the cell membrane. However, the molecular identity of the necroptotic membrane pore...

Alternative Titles

Full title

Ca super(2+) signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1859501836

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1859501836

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-016-2338-3

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