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Precise and efficient scarless genome editing in stem cells using CORRECT

Precise and efficient scarless genome editing in stem cells using CORRECT

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1861578326

Precise and efficient scarless genome editing in stem cells using CORRECT

About this item

Full title

Precise and efficient scarless genome editing in stem cells using CORRECT

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2017-02, Vol.12 (2), p.329-354

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

CORRECT is a method comprising two variants, re-Guide and re-Cas, that enables efficient and scarless CRISPR/Cas9-based genome editing in hPSCs by introducing blocking mutations that hamper the re-editing of modified loci by Cas9.
CRISPR/Cas9 is a promising tool for genome-editing DNA in cells with single-base-pair precision, which allows novel<...

Alternative Titles

Full title

Precise and efficient scarless genome editing in stem cells using CORRECT

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1861578326

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1861578326

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/nprot.2016.171

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