Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
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Author / Creator
Mosteiro, Lluc , Pantoja, Cristina , Alcazar, Noelia , Marión, Rosa M. , Chondronasiou, Dafni , Rovira, Miguel , Fernandez-Marcos, Pablo J. , Muñoz-Martin, Maribel , Blanco-Aparicio, Carmen , Pastor, Joaquin , Gómez-López, Gonzalo , De Martino, Alba , Blasco, Maria A. , Abad, María and Serrano, Manuel
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
Differentiated cells in a culture dish can assume a new identity when manipulated to express four transcription factors. This “reprogramming” process has sparked interest because conceivably it could be harnessed as a therapeutic strategy for tissue regeneration. Mosteiro
et al.
used a mouse model to study the signals that promote cell reprog...
Alternative Titles
Full title
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
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TN_cdi_proquest_miscellaneous_1864526827
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1864526827
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaf4445
