IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex
IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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We report here the identification of a ligand-receptor system that, upon engagement, leads to the establishment of an antiviral state. Three closely positioned genes on human chromosome 19 encode distinct but paralogous proteins, which we designate interferon-λ1 (IFN-λ1), IFN-λ2 and IFN-λ3 (tentatively designated as IL-29, IL-28A and IL-28B, respec...
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Full title
IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex
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TN_cdi_proquest_miscellaneous_18666949
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18666949
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni875
