Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangiti...
Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study
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Author / Creator
Hegade, Vinod S, Dr , Kendrick, Stuart F W, PhD , Dobbins, Robert L, MD , Miller, Sam R, MSc , Thompson, Douglas, PhD , Richards, Duncan, FRCP , Storey, James, PhD , Dukes, George E, PharmD , Corrigan, Margaret, MRCP , Oude Elferink, Ronald P J, PhD , Beuers, Ulrich, Prof , Hirschfield, Gideon M, Prof and Jones, David E, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Up to 70% of patients with primary biliary cholangitis develop pruritus (itch) during the course of their disease. Treatment of pruritus in primary biliary cholangitis is challenging and novel therapies are needed. Ursodeoxycholic acid, the standard first-line treatment for primary biliary cholangitis, is largely ineffective for...
Alternative Titles
Full title
Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study
Authors, Artists and Contributors
Author / Creator
Kendrick, Stuart F W, PhD
Dobbins, Robert L, MD
Miller, Sam R, MSc
Thompson, Douglas, PhD
Richards, Duncan, FRCP
Storey, James, PhD
Dukes, George E, PharmD
Corrigan, Margaret, MRCP
Oude Elferink, Ronald P J, PhD
Beuers, Ulrich, Prof
Hirschfield, Gideon M, Prof
Jones, David E, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1867538421
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1867538421
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(17)30319-7