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Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-c...

Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1868327393

Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-cadherin axis

About this item

Full title

Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-cadherin axis

Publisher

London: Nature Publishing Group UK

Journal title

Bone marrow transplantation (Basingstoke), 2017-02, Vol.52 (2), p.245-251

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recombinant human soluble thrombomodulin (rTM) counteracted capillary leakage and alleviated edema in individuals with sinusoidal obstruction syndrome and engraftment syndrome after hematopoietic stem cell transplantation. We previously showed that rTM increased levels of antiapoptotic protein Mcl-1 and protected endothelial cells from calcineurin...

Alternative Titles

Full title

Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-cadherin axis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1868327393

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1868327393

Other Identifiers

ISSN

0268-3369

E-ISSN

1476-5365

DOI

10.1038/bmt.2016.241

How to access this item