Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-c...
Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-cadherin axis
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Author / Creator
Ikezoe, T , Yang, J , Nishioka, C , Umezawa, K and Yokoyama, A
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Recombinant human soluble thrombomodulin (rTM) counteracted capillary leakage and alleviated edema in individuals with sinusoidal obstruction syndrome and engraftment syndrome after hematopoietic stem cell transplantation. We previously showed that rTM increased levels of antiapoptotic protein Mcl-1 and protected endothelial cells from calcineurin...
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Full title
Thrombomodulin blocks calcineurin inhibitor-induced vascular permeability via inhibition of Src/VE-cadherin axis
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Record Identifier
TN_cdi_proquest_miscellaneous_1868327393
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1868327393
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ISSN
0268-3369
E-ISSN
1476-5365
DOI
10.1038/bmt.2016.241