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Dosage of Fgf8 Determines Whether Cell Survival Is Positively or Negatively Regulated in the Develop...

Dosage of Fgf8 Determines Whether Cell Survival Is Positively or Negatively Regulated in the Develop...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18687496

Dosage of Fgf8 Determines Whether Cell Survival Is Positively or Negatively Regulated in the Developing Forebrain

About this item

Full title

Dosage of Fgf8 Determines Whether Cell Survival Is Positively or Negatively Regulated in the Developing Forebrain

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1757-1762

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

FGF8 is known to be an important regulator of forebrain development. Here, we investigated the effects of varying the level of Fgf8 expression in the mouse forebrain. We detected two distinct responses, one that was proportionate with Fgf8 expression and another that was not. The latter response, which led to effects on cell survival, displayed a p...

Alternative Titles

Full title

Dosage of Fgf8 Determines Whether Cell Survival Is Positively or Negatively Regulated in the Developing Forebrain

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_18687496

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18687496

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0337736100

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