Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal patho...
Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial
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Author / Creator
Huttner, Angela, Dr , Hatz, Christoph, Prof , van den Dobbelsteen, Germie, PhD , Abbanat, Darren, PhD , Hornacek, Alena, MSc , Frölich, Rahel, BSc , Dreyer, Anita M, PhD , Martin, Patricia, PhD , Davies, Todd, PhD , Fae, Kellen, PhD , van den Nieuwenhof, Ingrid, PhD , Thoelen, Stefan, MD , de Vallière, Serge, MD , Kuhn, Anette, Prof , Bernasconi, Enos, MD , Viereck, Volker, Prof , Kavvadias, Tilemachos, MD , Kling, Kerstin, MD , Ryu, Gloria, MD , Hülder, Tanja, MD , Gröger, Sabine, MD , Scheiner, David, MD , Alaimo, Cristina, PhD , Harbarth, Stephan, MD , Poolman, Jan, PhD and Fonck, Veronica Gambillara, PhD
Publisher
United States: Elsevier Ltd
Journal title
Language
English
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Publisher
United States: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Escherichia coli infections are increasing worldwide in community and hospital settings. The E coli O-antigen is a promising vaccine target. We aimed to assess the safety and immunogenicity of a bioconjugate vaccine containing the O-antigens of four E coli serotypes (ExPEC4V). Methods In this multicentre phase 1b, first-in-human,...
Alternative Titles
Full title
Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial
Authors, Artists and Contributors
Author / Creator
Hatz, Christoph, Prof
van den Dobbelsteen, Germie, PhD
Abbanat, Darren, PhD
Hornacek, Alena, MSc
Frölich, Rahel, BSc
Dreyer, Anita M, PhD
Martin, Patricia, PhD
Davies, Todd, PhD
Fae, Kellen, PhD
van den Nieuwenhof, Ingrid, PhD
Thoelen, Stefan, MD
de Vallière, Serge, MD
Kuhn, Anette, Prof
Bernasconi, Enos, MD
Viereck, Volker, Prof
Kavvadias, Tilemachos, MD
Kling, Kerstin, MD
Ryu, Gloria, MD
Hülder, Tanja, MD
Gröger, Sabine, MD
Scheiner, David, MD
Alaimo, Cristina, PhD
Harbarth, Stephan, MD
Poolman, Jan, PhD
Fonck, Veronica Gambillara, PhD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1872581645
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872581645
Other Identifiers
ISSN
1473-3099
E-ISSN
1474-4457
DOI
10.1016/S1473-3099(17)30108-1
