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Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADA...

Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADA...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872814139

Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10

About this item

Full title

Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2017-03, Vol.18 (3), p.313-320

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The signaling receptor Notch is required for the generation of marginal zone B cells. Hammad and colleagues show that Notch signaling activates the kinase Taok3 and surface expression of the metalloproteinase ADAM10, which commits transitional B cells to the marginal zone B cell fate.
Notch2 and B cell antigen receptor (BCR) signaling determine...

Alternative Titles

Full title

Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1872814139

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872814139

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3657

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