A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease
A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease
About this item
Full title
Author / Creator
Pelczar, Penelope , Witkowski, Mario , Perez, Laura Garcia , Kempski, Jan , Hammel, Anna G. , Brockmann, Leonie , Kleinschmidt, Dörte , Wende, Sandra , Haueis, Cathleen , Bedke, Tanja , Witkowski, Marco , Krasemann, Susanne , Steurer, Stefan , Booth, Carmen J. , Busch, Philipp , König, Alexandra , Rauch, Ursula , Benten, Daniel , Izbicki, Jakob R. , Rösch, Thomas , Lohse, Ansgar W. , Strowig, Till , Gagliani, Nicola , Flavell, Richard A. and Huber, Samuel
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Intestinal inflammation can impair mucosal healing, thereby establishing a vicious cycle leading to chronic inflammatory bowel disease (IBD). However, the signaling networks driving chronic inflammation remain unclear. Here we report that CD4⁺ T cells isolated from patients with IBD produce high levels of interleukin-22 binding protein (IL-22BP), t...
Alternative Titles
Full title
A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease
Authors, Artists and Contributors
Author / Creator
Witkowski, Mario
Perez, Laura Garcia
Kempski, Jan
Hammel, Anna G.
Brockmann, Leonie
Kleinschmidt, Dörte
Wende, Sandra
Haueis, Cathleen
Bedke, Tanja
Witkowski, Marco
Krasemann, Susanne
Steurer, Stefan
Booth, Carmen J.
Busch, Philipp
König, Alexandra
Rauch, Ursula
Benten, Daniel
Izbicki, Jakob R.
Rösch, Thomas
Lohse, Ansgar W.
Strowig, Till
Gagliani, Nicola
Flavell, Richard A.
Huber, Samuel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1872829822
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872829822
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aah5903
