Discovering Anti-platelet Drug Combinations with an Integrated Model of Activator-Inhibitor Relation...
Discovering Anti-platelet Drug Combinations with an Integrated Model of Activator-Inhibitor Relationships, Activator-Activator Synergies and Inhibitor-Inhibitor Synergies: e1004119
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Contents
Identifying effective therapeutic drug combinations that modulate complex signaling pathways in platelets is central to the advancement of effective anti-thrombotic therapies. However, there is no systems model of the platelet that predicts responses to different inhibitor combinations. We developed an approach which goes beyond current inhibitor-i...
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Full title
Discovering Anti-platelet Drug Combinations with an Integrated Model of Activator-Inhibitor Relationships, Activator-Activator Synergies and Inhibitor-Inhibitor Synergies: e1004119
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TN_cdi_proquest_miscellaneous_1872833449
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872833449
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ISSN
1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1004119