How do metal ions direct ribozyme folding?
How do metal ions direct ribozyme folding?
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Ribozymes, which carry out phosphoryl-transfer reactions, often require Mg
2+
ions for catalytic activity. The correct folding of the active site and ribozyme tertiary structure is also regulated by metal ions in a manner that is not fully understood. Here we employ coarse-grained molecular simulations to show that individual structural eleme...
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Full title
How do metal ions direct ribozyme folding?
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TN_cdi_proquest_miscellaneous_1872839326
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872839326
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2330
