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Next-generation sequencing indicates false-positive MRD results and better predicts prognosis after...

Next-generation sequencing indicates false-positive MRD results and better predicts prognosis after...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872888464

Next-generation sequencing indicates false-positive MRD results and better predicts prognosis after SCT in patients with childhood ALL

About this item

Full title

Next-generation sequencing indicates false-positive MRD results and better predicts prognosis after SCT in patients with childhood ALL

Publisher

London: Nature Publishing Group UK

Journal title

Bone marrow transplantation (Basingstoke), 2017-07, Vol.52 (7), p.962-968

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Minimal residual disease (MRD) monitoring via quantitative PCR (qPCR) detection of Ag receptor gene rearrangements has been the most sensitive method for predicting prognosis and making post-transplant treatment decisions for patients with ALL. Despite the broad clinical usefulness and standardization of this method, we and others have repeatedly r...

Alternative Titles

Full title

Next-generation sequencing indicates false-positive MRD results and better predicts prognosis after SCT in patients with childhood ALL

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1872888464

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1872888464

Other Identifiers

ISSN

0268-3369

E-ISSN

1476-5365

DOI

10.1038/bmt.2017.16

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