Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasizat...
Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
The inhibition of Delta-like 4 (Dll4)/Notch signaling has been shown to result in excessive, nonfunctional vessel proliferation and significant tumor growth suppression. However, safety concerns emerged with the identification of side effects resulting from chronic Dll4/Notch blockade. Alternatively, we explored the endothelial Dll4 overexpression...
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Full title
Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo
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TN_cdi_proquest_miscellaneous_1877526052
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1877526052
Other Identifiers
E-ISSN
1471-2407
DOI
10.1186/s12885-017-3171-2
