4μ8C Inhibits Insulin Secretion Independent of IRE1α RNase Activity
4μ8C Inhibits Insulin Secretion Independent of IRE1α RNase Activity
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Japan: Japan Society for Cell Biology
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Language
English
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Japan: Japan Society for Cell Biology
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Contents
IRE1α plays an important role in the unfolded protein response (UPR), which is activated by the accumulation of unfolded proteins in the endoplasmic reticulum. 4μ8C, a well-known inhibitor of IRE1α RNase activity, is commonly used to analyze IRE1α function during ER stress in cultured mammalian cells. However, the off-target effects of 4μ8C remain...
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Full title
4μ8C Inhibits Insulin Secretion Independent of IRE1α RNase Activity
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TN_cdi_proquest_miscellaneous_1879663812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1879663812
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ISSN
0386-7196
E-ISSN
1347-3700
DOI
10.1247/csf.17002
