Hepatocyte growth factor induces apoptosis through the extrinsic pathway in hepatoma cells: favourin...
Hepatocyte growth factor induces apoptosis through the extrinsic pathway in hepatoma cells: favouring role of hypoxia-inducible factor-1 deficiency
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Two hepatocarcinoma cell lines, the Hepa-1 wild-type (c1c7) and the
β
-subunit mutated (c4) lacking hypoxia-inducible factor-1 (HIF-1) activity, were differentially susceptible to apoptosis by hepatocyte growth factor (HGF). The c4 cells were 40% apoptotic 48 h after HGF treatment. On the contrary, the wild-type c1c7 cells showed modest signs...
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Full title
Hepatocyte growth factor induces apoptosis through the extrinsic pathway in hepatoma cells: favouring role of hypoxia-inducible factor-1 deficiency
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TN_cdi_proquest_miscellaneous_18800731
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18800731
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1206519
