Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells
Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells
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Author / Creator
Hu, Guanzheng , Gong, Xiaoli , Wang, Le , Liu, Mengru , Liu, Yang , Fu, Xia , Wang, Wei , Zhang, Ting and Wang, Xiaomin
Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Contents
Parkinson’s disease (PD) is an aging-associated neurodegenerative disease with a characteristic feature of α-synuclein accumulation. Point mutations (A53T, A30P) that increase the aggregation propensity of α-synuclein result in familial early onset PD. The abnormal metabolism of α-synuclein results in aberrant level changes of α-synuclein in PD. In...
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Full title
Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells
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Record Identifier
TN_cdi_proquest_miscellaneous_1881760391
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1881760391
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-016-9808-3
