2-Acetyl-5-tetrahydroxybutyl imidazole (THI) protects 661W cells against oxidative stress
2-Acetyl-5-tetrahydroxybutyl imidazole (THI) protects 661W cells against oxidative stress
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Retinal degeneration and in particular retinitis pigmentosa (RP) is associated to ceramide (Cer) accumulation and cell death induction. Cer and sphingosine-1-phosphate (S1P) belong to the sphingolipids class and exert a pro-apoptotic and pro-survival activity, respectively. Our aim is to target sphingolipid metabolism by inhibiting S1P lyase that r...
Alternative Titles
Full title
2-Acetyl-5-tetrahydroxybutyl imidazole (THI) protects 661W cells against oxidative stress
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1888682628
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1888682628
Other Identifiers
ISSN
0028-1298
E-ISSN
1432-1912
DOI
10.1007/s00210-017-1374-3
