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Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependen...

Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1888974837

Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependent manner

About this item

Full title

Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependent manner

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cell and tissue research, 2017-04, Vol.368 (1), p.135-144

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Osteoarthritis is a degenerative joint disease caused by excessive death of chondrocytes and loss of the extracellular matrix (ECM) in articular cartilage. We previously reported that reactive oxygen species (ROS) generated by the NADPH oxidase (NOX) isoform NOX-2 are involved in chondrocyte death induced by interleukin-1β (IL-1β). In this study, w...

Alternative Titles

Full title

Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependent manner

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1888974837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1888974837

Other Identifiers

ISSN

0302-766X

E-ISSN

1432-0878

DOI

10.1007/s00441-016-2551-2

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