In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs
In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Purpose
In view of pediatric drug development, juvenile animal studies are gaining importance. However, data on drug metabolizing capacities of juvenile animals are scarce, especially in non-rodent species. Therefore, we aimed to characterize the
in vitro
biotransformation of four human CYP450 substrates and one UGT substrate in the livers...
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Full title
In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs
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TN_cdi_proquest_miscellaneous_1888975494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1888975494
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-017-2101-y
