Marker-free coselection for CRISPR-driven genome editing in human cells
Marker-free coselection for CRISPR-driven genome editing in human cells
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
A gain-of-function mutation in a sodium/potassium pump renders cells resistant to a small-molecule drug and provides an efficient coselection strategy to enrich for CRISPR-induced mutations at an independent locus.
Targeted genome editing enables the creation of bona fide cellular models for biological research and may be applied to human cell-b...
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Full title
Marker-free coselection for CRISPR-driven genome editing in human cells
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TN_cdi_proquest_miscellaneous_1889384056
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1889384056
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.4265
