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Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem c...

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1891455630

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells

About this item

Full title

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2017-06, Vol.24 (6), p.515-524

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Homotypic interactions between active and Polycomb-repressed promoters co-occurring in the same DNA fiber, rather than CTCF occupancy, explain the 3D HoxB folding pattern.
Gene expression states influence the 3D conformation of the genome through poorly understood mechanisms. Here, we investigate the conformation of the murine
HoxB
locus,...

Alternative Titles

Full title

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1891455630

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1891455630

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.3402

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