Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem c...
Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Homotypic interactions between active and Polycomb-repressed promoters co-occurring in the same DNA fiber, rather than CTCF occupancy, explain the 3D HoxB folding pattern.
Gene expression states influence the 3D conformation of the genome through poorly understood mechanisms. Here, we investigate the conformation of the murine
HoxB
locus,...
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Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells
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TN_cdi_proquest_miscellaneous_1891455630
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1891455630
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3402