Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with com...
Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors
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Publisher
England: Future Medicine Ltd
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Language
English
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Publisher
England: Future Medicine Ltd
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Scope and Contents
Contents
One concern in epigenome-wide studies investigating leukocyte DNA methylation is that observed associations may at least partly reflect differences in leukocyte composition (LC) rather than changes in methylation. We estimated the magnitude of confounding by LC for common risk factors and diseases.
Variation of LC according to sex, race, age, sm...
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Full title
Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors
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TN_cdi_proquest_miscellaneous_1895278343
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1895278343
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ISSN
1750-1911
E-ISSN
1750-192X
DOI
10.2217/epi-2016-0154