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Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with com...

Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with com...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1895278343

Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors

About this item

Full title

Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors

Publisher

England: Future Medicine Ltd

Journal title

Epigenomics, 2017-05, Vol.9 (5), p.659-668

Language

English

Formats

Publication information

Publisher

England: Future Medicine Ltd

More information

Scope and Contents

Contents

One concern in epigenome-wide studies investigating leukocyte DNA methylation is that observed associations may at least partly reflect differences in leukocyte composition (LC) rather than changes in methylation. We estimated the magnitude of confounding by LC for common risk factors and diseases.
Variation of LC according to sex, race, age, sm...

Alternative Titles

Full title

Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1895278343

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1895278343

Other Identifiers

ISSN

1750-1911

E-ISSN

1750-192X

DOI

10.2217/epi-2016-0154

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