A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals:...
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium
About this item
Full title
Author / Creator
Noordam, Raymond , Sitlani, Colleen M , Avery, Christy L , Stewart, James D , Gogarten, Stephanie M , Wiggins, Kerri L , Trompet, Stella , Warren, Helen R , Sun, Fangui , Evans, Daniel S , Li, Xiaohui , Li, Jin , Smith, Albert V , Bis, Joshua C , Brody, Jennifer A , Busch, Evan L , Caulfield, Mark J , Chen, Yii-Der I , Cummings, Steven R , Cupples, L Adrienne , Duan, Qing , Franco, Oscar H , Méndez-Giráldez, Rául , Harris, Tamara B , Heckbert, Susan R , van Heemst, Diana , Hofman, Albert , Floyd, James S , Kors, Jan A , Launer, Lenore J , Li, Yun , Li-Gao, Ruifang , Lange, Leslie A , Lin, Henry J , de Mutsert, Renée , Napier, Melanie D , Newton-Cheh, Christopher , Poulter, Neil , Reiner, Alexander P , Rice, Kenneth M , Roach, Jeffrey , Rodriguez, Carlos J , Rosendaal, Frits R , Sattar, Naveed , Sever, Peter , Seyerle, Amanda A , Slagboom, P Eline , Soliman, Elsayed Z , Sotoodehnia, Nona , Stott, David J , Stürmer, Til , Taylor, Kent D , Thornton, Timothy A , Uitterlinden, André G , Wilhelmsen, Kirk C , Wilson, James G , Gudnason, Vilmundur , Jukema, J Wouter , Laurie, Cathy C , Liu, Yongmei , Mook-Kanamori, Dennis O , Munroe, Patricia B , Rotter, Jerome I , Vasan, Ramachandran S , Psaty, Bruce M , Stricker, Bruno H and Whitsel, Eric A
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundIncreased heart rate and a prolonged QT interval are important risk factors for cardiovascular morbidity and mortality, and can be influenced by the use of various medications, including tricyclic/tetracyclic antidepressants (TCAs). We aim to identify genetic loci that modify the association between TCA use and RR and QT intervals.Methods...
Alternative Titles
Full title
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium
Authors, Artists and Contributors
Author / Creator
Sitlani, Colleen M
Avery, Christy L
Stewart, James D
Gogarten, Stephanie M
Wiggins, Kerri L
Trompet, Stella
Warren, Helen R
Sun, Fangui
Evans, Daniel S
Li, Xiaohui
Li, Jin
Smith, Albert V
Bis, Joshua C
Brody, Jennifer A
Busch, Evan L
Caulfield, Mark J
Chen, Yii-Der I
Cummings, Steven R
Cupples, L Adrienne
Duan, Qing
Franco, Oscar H
Méndez-Giráldez, Rául
Harris, Tamara B
Heckbert, Susan R
van Heemst, Diana
Hofman, Albert
Floyd, James S
Kors, Jan A
Launer, Lenore J
Li, Yun
Li-Gao, Ruifang
Lange, Leslie A
Lin, Henry J
de Mutsert, Renée
Napier, Melanie D
Newton-Cheh, Christopher
Poulter, Neil
Reiner, Alexander P
Rice, Kenneth M
Roach, Jeffrey
Rodriguez, Carlos J
Rosendaal, Frits R
Sattar, Naveed
Sever, Peter
Seyerle, Amanda A
Slagboom, P Eline
Soliman, Elsayed Z
Sotoodehnia, Nona
Stott, David J
Stürmer, Til
Taylor, Kent D
Thornton, Timothy A
Uitterlinden, André G
Wilhelmsen, Kirk C
Wilson, James G
Gudnason, Vilmundur
Jukema, J Wouter
Laurie, Cathy C
Liu, Yongmei
Mook-Kanamori, Dennis O
Munroe, Patricia B
Rotter, Jerome I
Vasan, Ramachandran S
Psaty, Bruce M
Stricker, Bruno H
Whitsel, Eric A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1897369078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1897369078
Other Identifiers
ISSN
0022-2593,1468-6244
E-ISSN
1468-6244
DOI
10.1136/jmedgenet-2016-104112
