The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic can...
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
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Author / Creator
Krebs, Angela M. , Mitschke, Julia , Lasierra Losada, María , Schmalhofer, Otto , Boerries, Melanie , Busch, Hauke , Boettcher, Martin , Mougiakakos, Dimitrios , Reichardt, Wilfried , Bronsert, Peter , Brunton, Valerie G. , Pilarsky, Christian , Winkler, Thomas H. , Brabletz, Simone , Stemmler, Marc P. and Brabletz, Thomas
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Metastasis is the major cause of cancer-associated death. Partial activation of the epithelial-to-mesenchymal transition program (partial EMT) was considered a major driver of tumour progression from initiation to metastasis. However, the role of EMT in promoting metastasis has recently been challenged, in particular concerning effects of the Snail...
Alternative Titles
Full title
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
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Record Identifier
TN_cdi_proquest_miscellaneous_1897370997
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1897370997
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3513
