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Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through S...

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through S...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1897375059

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

About this item

Full title

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

Publisher

Tokyo: Springer Japan

Journal title

International journal of hematology, 2017-05, Vol.105 (5), p.587-597

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

The poor prognosis of adults with B cell precursor acute lymphoblastic leukemia (BCP-ALL) is attributed to leukemia cells that are protected by the bone marrow (BM) microenvironment. In the present study, we explored the pharmacological targeting of mesenchymal stromal/stem cells in BM (BM-MSCs) to eliminate chemoresistant BCP-ALL cells. Human BCP-...

Alternative Titles

Full title

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1897375059

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1897375059

Other Identifiers

ISSN

0925-5710

E-ISSN

1865-3774

DOI

10.1007/s12185-016-2169-x

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