Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an o...
Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial
About this item
Full title
Author / Creator
Hida, Toyoaki, MD , Nokihara, Hiroshi, MD , Kondo, Masashi, MD , Kim, Young Hak, MD , Azuma, Koichi, MD , Seto, Takashi, MD , Takiguchi, Yuichi, Prof , Nishio, Makoto, MD , Yoshioka, Hiroshige, MD , Imamura, Fumio, MD , Hotta, Katsuyuki, Prof , Watanabe, Satoshi, MD , Goto, Koichi, MD , Satouchi, Miyako, MD , Kozuki, Toshiyuki, MD , Shukuya, Takehito, MD , Nakagawa, Kazuhiko, Prof , Mitsudomi, Tetsuya, Prof , Yamamoto, Nobuyuki, Prof , Asakawa, Takashi, PhD , Asabe, Ryoichi, MS , Tanaka, Tomohiro, MS and Tamura, Tomohide, Dr
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Alectinib, a potent, highly selective, CNS-active inhibitor of anaplastic lymphoma kinase (ALK), showed promising efficacy and tolerability in the single-arm phase 1/2 AF-001JP trial in Japanese patients with ALK -positive non-small-cell lung cancer. Given those promising results, we did a phase 3 trial to directly compare the ef...
Alternative Titles
Full title
Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial
Authors, Artists and Contributors
Author / Creator
Nokihara, Hiroshi, MD
Kondo, Masashi, MD
Kim, Young Hak, MD
Azuma, Koichi, MD
Seto, Takashi, MD
Takiguchi, Yuichi, Prof
Nishio, Makoto, MD
Yoshioka, Hiroshige, MD
Imamura, Fumio, MD
Hotta, Katsuyuki, Prof
Watanabe, Satoshi, MD
Goto, Koichi, MD
Satouchi, Miyako, MD
Kozuki, Toshiyuki, MD
Shukuya, Takehito, MD
Nakagawa, Kazuhiko, Prof
Mitsudomi, Tetsuya, Prof
Yamamoto, Nobuyuki, Prof
Asakawa, Takashi, PhD
Asabe, Ryoichi, MS
Tanaka, Tomohiro, MS
Tamura, Tomohide, Dr
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1899117490
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1899117490
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(17)30565-2
