Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in g...
Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients
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New York: Springer US
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Language
English
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New York: Springer US
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Resistance to temozolomide (TMZ) chemotherapy poses a significant challenge in the treatment of glioblastoma (GBM). Hypermethylation in O
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-methylguanine-DNA methyltransferase (MGMT) promoter is thought to play a critical role in this resistance. Pyrosequencing (PSQ) has been shown to be accurate and robust for MGMT promoter methylation test...
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Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients
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TN_cdi_proquest_miscellaneous_1900129423
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1900129423
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ISSN
0167-594X
E-ISSN
1573-7373
DOI
10.1007/s11060-017-2433-9
