Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-...
Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial
About this item
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Author / Creator
Vermeire, Séverine, Prof , Sandborn, William J, Prof , Danese, Silvio, Prof , Hébuterne, Xavier, Prof , Salzberg, Bruce A, MD , Klopocka, Maria, MD , Tarabar, Dino, MD , Vanasek, Tomas, MD , Greguš, Miloš, MD , Hellstern, Paul A, MD , Kim, Joo Sung, MD , Sparrow, Miles P, MBBS , Gorelick, Kenneth J, MD , Hinz, Michelle, MS , Ahmad, Alaa, PhD , Pradhan, Vivek, MS , Hassan-Zahraee, Mina, PhD , Clare, Robert, PhD , Cataldi, Fabio, MD and Reinisch, Walter, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background PF-00547659 is a fully human monoclonal antibody that binds to human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) to selectively reduce lymphocyte homing to the intestinal tract. We aimed to assess the efficacy and safety of PF-00547659 in patients with moderate to severe ulcerative colitis. Methods This phase 2, randomi...
Alternative Titles
Full title
Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial
Authors, Artists and Contributors
Author / Creator
Sandborn, William J, Prof
Danese, Silvio, Prof
Hébuterne, Xavier, Prof
Salzberg, Bruce A, MD
Klopocka, Maria, MD
Tarabar, Dino, MD
Vanasek, Tomas, MD
Greguš, Miloš, MD
Hellstern, Paul A, MD
Kim, Joo Sung, MD
Sparrow, Miles P, MBBS
Gorelick, Kenneth J, MD
Hinz, Michelle, MS
Ahmad, Alaa, PhD
Pradhan, Vivek, MS
Hassan-Zahraee, Mina, PhD
Clare, Robert, PhD
Cataldi, Fabio, MD
Reinisch, Walter, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1901308914
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1901308914
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(17)30930-3
