Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
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New York: Springer New York
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Language
English
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New York: Springer New York
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Contents
Targeted editing of single base pairs is achieved in monocot rice and dicot tomato using Target-AID (Cas9 activation-induced cytidine deaminase fusion).
We applied a fusion of CRISPR-Cas9 and activation-induced cytidine deaminase (Target-AID) for point mutagenesis at genomic regions specified by single guide RNAs (sgRNAs) in two crop plants. In...
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Full title
Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
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TN_cdi_proquest_miscellaneous_1901760888
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1901760888
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3833
