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A molecular census of 26S proteasomes in intact neurons

A molecular census of 26S proteasomes in intact neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904251156

A molecular census of 26S proteasomes in intact neurons

About this item

Full title

A molecular census of 26S proteasomes in intact neurons

Publisher

Washington: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2015-01, Vol.347 (6220), p.439-442

Language

English

Formats

Publication information

Publisher

Washington: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The 26S proteasome is a key player in eukaryotic protein quality control and in the regulation of numerous cellular processes. Here, we describe quantitative in situ structural studies of this highly dynamic molecular machine in intact hippocampal neurons. We used electron cryotomography with the Volta phase plate, which allowed high fidelity and n...

Alternative Titles

Full title

A molecular census of 26S proteasomes in intact neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1904251156

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904251156

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1261197

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