A molecular census of 26S proteasomes in intact neurons
A molecular census of 26S proteasomes in intact neurons
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Publisher
Washington: American Association for the Advancement of Science
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Language
English
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Publisher
Washington: American Association for the Advancement of Science
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Contents
The 26S proteasome is a key player in eukaryotic protein quality control and in the regulation of numerous cellular processes. Here, we describe quantitative in situ structural studies of this highly dynamic molecular machine in intact hippocampal neurons. We used electron cryotomography with the Volta phase plate, which allowed high fidelity and n...
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Full title
A molecular census of 26S proteasomes in intact neurons
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TN_cdi_proquest_miscellaneous_1904251156
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904251156
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1261197