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The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904908601

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

About this item

Full title

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-06, Vol.546 (7657), p.302-306

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Combined studies in MYC-driven mouse lymphomas and human Burkitt lymphoma unravel an essential role for the B-cell antigen receptor in the control of tumour B-cell fitness both
in vitro
and
in vivo
, with possible biological and clinical implications.
BCR signalling gives lymphoma competitive advantage
The B-cell receptor (BCR) co...

Alternative Titles

Full title

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1904908601

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1904908601

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature22353

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