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TGF-β1 Improves Biomechanical Strength by Extracellular Matrix Accumulation Without Increasing the N...

TGF-β1 Improves Biomechanical Strength by Extracellular Matrix Accumulation Without Increasing the N...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1907000483

TGF-β1 Improves Biomechanical Strength by Extracellular Matrix Accumulation Without Increasing the Number of Tenogenic Lineage Cells in a Rat Rotator Cuff Repair Model

About this item

Full title

TGF-β1 Improves Biomechanical Strength by Extracellular Matrix Accumulation Without Increasing the Number of Tenogenic Lineage Cells in a Rat Rotator Cuff Repair Model

Publisher

Los Angeles, CA: SAGE Publications

Journal title

The American journal of sports medicine, 2017-08, Vol.45 (10), p.2394-2404

Language

English

Formats

Publication information

Publisher

Los Angeles, CA: SAGE Publications

More information

Scope and Contents

Contents

Background:
Transforming growth factor β1 (TGF-β1) positively regulates the tenogenic marker genes scleraxis (Scx) and tenomodulin (Tnmd) in mesenchymal progenitors in vitro. However, little is known about the effect of TGF-β1 on the expression of tenogenic markers during rotator cuff (RC) healing in rats.
Hypothesis:
TGF-β1 improves the b...

Alternative Titles

Full title

TGF-β1 Improves Biomechanical Strength by Extracellular Matrix Accumulation Without Increasing the Number of Tenogenic Lineage Cells in a Rat Rotator Cuff Repair Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1907000483

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1907000483

Other Identifiers

ISSN

0363-5465

E-ISSN

1552-3365

DOI

10.1177/0363546517707940

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