Log in to save to my catalogue

Challenges in longitudinal exposure-response modeling of data from complex study designs: a case stu...

Challenges in longitudinal exposure-response modeling of data from complex study designs: a case stu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1910800746

Challenges in longitudinal exposure-response modeling of data from complex study designs: a case study of modeling CDAI score for ustekinumab in patients with Crohn’s disease

About this item

Full title

Challenges in longitudinal exposure-response modeling of data from complex study designs: a case study of modeling CDAI score for ustekinumab in patients with Crohn’s disease

Publisher

New York: Springer US

Journal title

Journal of pharmacokinetics and pharmacodynamics, 2017-10, Vol.44 (5), p.425-436

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Informative exposure-response modeling of clinical endpoints is important in drug development to identify optimum dose and dosing regimens. Despite much recent progress in mechanism-based longitudinal modeling of clinical data, challenges remain in clinical trials of diseases such as Crohn’s disease, where a commonly used composite endpoint Crohn’s...

Alternative Titles

Full title

Challenges in longitudinal exposure-response modeling of data from complex study designs: a case study of modeling CDAI score for ustekinumab in patients with Crohn’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1910800746

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1910800746

Other Identifiers

ISSN

1567-567X

E-ISSN

1573-8744

DOI

10.1007/s10928-017-9529-x

How to access this item