Challenges in longitudinal exposure-response modeling of data from complex study designs: a case stu...
Challenges in longitudinal exposure-response modeling of data from complex study designs: a case study of modeling CDAI score for ustekinumab in patients with Crohn’s disease
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New York: Springer US
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English
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New York: Springer US
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Informative exposure-response modeling of clinical endpoints is important in drug development to identify optimum dose and dosing regimens. Despite much recent progress in mechanism-based longitudinal modeling of clinical data, challenges remain in clinical trials of diseases such as Crohn’s disease, where a commonly used composite endpoint Crohn’s...
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Challenges in longitudinal exposure-response modeling of data from complex study designs: a case study of modeling CDAI score for ustekinumab in patients with Crohn’s disease
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TN_cdi_proquest_miscellaneous_1910800746
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1910800746
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ISSN
1567-567X
E-ISSN
1573-8744
DOI
10.1007/s10928-017-9529-x