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T cells from patients with Parkinson’s disease recognize α-synuclein peptides

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1912607988

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

About this item

Full title

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-06, Vol.546 (7660), p.656-661

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Epitopes derived from two regions of α-synuclein elicit immune responses in patients with Parkinson’s disease, involving IL-5-secreting CD4
+
T cells, as well as IFNγ-secreting CD8
+
cytotoxic T cells.
A possible immune component to Parkinson's disease
Major pathological hallmarks of Parkinson's disease are the death of neurons in...

Alternative Titles

Full title

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1912607988

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1912607988

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature22815

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