mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate
mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
Nutrient sensing by mechanistic target of rapamycin complex 1 (mTORC1) on lysosomes and late endosomes (LyLEs) regulates cell growth. Many factors stimulate mTORC1 activity, including the production of phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P3] by class I phosphatidylinositol 3-kinases (PI3Ks) at the plasma membrane. We investigated mec...
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Full title
mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate
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Record Identifier
TN_cdi_proquest_miscellaneous_1915324023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1915324023
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaf8310
