ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice
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United States: American Association for the Advancement of Science
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Language
English
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United States: American Association for the Advancement of Science
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Preeclampsia (PE) is a gestational hypertensive syndrome affecting between 5 and 8% of all pregnancies. Although PE is the leading cause of fetal and maternal morbidity and mortality, its molecular etiology is still unclear. Here, we show that ELABELA (ELA), an endogenous ligand of the apelin receptor (APLNR, or APJ), is a circulating hormone secre...
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Full title
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice
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TN_cdi_proquest_miscellaneous_1915343409
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1915343409
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aam6607
