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Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice

Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1915344926

Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice

About this item

Full title

Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice

Publisher

Vienna: Springer Vienna

Journal title

Archives of virology, 2017-10, Vol.162 (10), p.3017-3024

Language

English

Formats

Publication information

Publisher

Vienna: Springer Vienna

More information

Scope and Contents

Contents

Influenza A viruses must undergo adaptation to acquire virulence in new host species. In mouse models, host adaptation for virulence is generally performed through 5 to 20 lung-to-lung passages. However, highly pathogenic avian influenza viruses (e.g., H5N1 and H7N7 subtypes) have been observed to acquire virulence in mice after only a few
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Alternative Titles

Full title

Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1915344926

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1915344926

Other Identifiers

ISSN

0304-8608

E-ISSN

1432-8798

DOI

10.1007/s00705-017-3451-9

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