Reduced TRPC6 mRNA levels in the blood cells of patients with Alzheimer’s disease and mild cognitive...
Reduced TRPC6 mRNA levels in the blood cells of patients with Alzheimer’s disease and mild cognitive impairment
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Transient receptor potential canonical 6 (TRPC6) inhibits β-amyloid (Aβ) production. Hyperforin, the TRPC6 agonist, reduces Aβ levels and improves cognitive performance in Alzheimer’s disease (AD) models. However, it’s unknown whether TRPC6 expression is changed in AD patients. In this case–control study, we measured TRPC6 expression levels in the...
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Reduced TRPC6 mRNA levels in the blood cells of patients with Alzheimer’s disease and mild cognitive impairment
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TN_cdi_proquest_miscellaneous_1917962714
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1917962714
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/mp.2017.136