Dll4 and Notch signalling couples sprouting angiogenesis and artery formation
Dll4 and Notch signalling couples sprouting angiogenesis and artery formation
About this item
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Author / Creator
Pitulescu, Mara E. , Schmidt, Inga , Giaimo, Benedetto Daniele , Antoine, Tobiah , Berkenfeld, Frank , Ferrante, Francesca , Park, Hongryeol , Ehling, Manuel , Biljes, Daniel , Rocha, Susana F. , Langen, Urs H. , Stehling, Martin , Nagasawa, Takashi , Ferrara, Napoleone , Borggrefe, Tilman and Adams, Ralf H.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Endothelial sprouting and proliferation are tightly coordinated processes mediating the formation of new blood vessels during physiological and pathological angiogenesis. Endothelial tip cells lead sprouts and are thought to suppress tip-like behaviour in adjacent stalk endothelial cells by activating Notch. Here, we show with genetic experiments i...
Alternative Titles
Full title
Dll4 and Notch signalling couples sprouting angiogenesis and artery formation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1920194354
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1920194354
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3555
