Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer...
Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial
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Author / Creator
Pujade-Lauraine, Eric, Prof , Ledermann, Jonathan A, Prof , Selle, Frédéric, MD , Gebski, Val, Prof , Penson, Richard T, MD , Oza, Amit M, Prof , Korach, Jacob, MD , Huzarski, Tomasz, MD , Poveda, Andrés, MD , Pignata, Sandro, Prof , Friedlander, Michael, Prof , Colombo, Nicoletta, Prof , Harter, Philipp, MD , Fujiwara, Keiichi, Prof , Ray-Coquard, Isabelle, Prof , Banerjee, Susana, PhD , Liu, Joyce, MD , Lowe, Elizabeth S, MD , Bloomfield, Ralph, MSc , Pautier, Patricia, MD and SOLO2/ENGOT-Ov21 investigators
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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More information
Scope and Contents
Contents
SummaryBackgroundOlaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor, has previously shown efficacy in a phase 2 study when given in capsule formulation to all-comer patients with platinum-sensitive, relapsed high-grade serous ovarian cancer. We aimed to confirm these findings in patients with a BRCA1 or BRCA2 (BRCA1/2) mutation using a tablet...
Alternative Titles
Full title
Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Ledermann, Jonathan A, Prof
Selle, Frédéric, MD
Gebski, Val, Prof
Penson, Richard T, MD
Oza, Amit M, Prof
Korach, Jacob, MD
Huzarski, Tomasz, MD
Poveda, Andrés, MD
Pignata, Sandro, Prof
Friedlander, Michael, Prof
Colombo, Nicoletta, Prof
Harter, Philipp, MD
Fujiwara, Keiichi, Prof
Ray-Coquard, Isabelle, Prof
Banerjee, Susana, PhD
Liu, Joyce, MD
Lowe, Elizabeth S, MD
Bloomfield, Ralph, MSc
Pautier, Patricia, MD
SOLO2/ENGOT-Ov21 investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1924601115
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1924601115
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(17)30469-2
