Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Rec...
Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression
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Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Contents
Dopamine D
2
receptor (D
2
R) activation triggers both G protein- and β-arrestin-dependent signaling. Biased D
2
R ligands activating β-arrestin pathway have been proposed as potential antipsychotics. The ability of D
2
R to heteromerize with adenosine A
2A
receptor (A
2A
R) has been associated to D
2
R ago...
Alternative Titles
Full title
Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression
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TN_cdi_proquest_miscellaneous_1926687498
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1926687498
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-017-0696-y