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Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Rec...

Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Rec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1926687498

Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression

About this item

Full title

Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression

Publisher

New York: Springer US

Journal title

Molecular neurobiology, 2018-06, Vol.55 (6), p.4952-4958

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Dopamine D
2
receptor (D
2
R) activation triggers both G protein- and β-arrestin-dependent signaling. Biased D
2
R ligands activating β-arrestin pathway have been proposed as potential antipsychotics. The ability of D
2
R to heteromerize with adenosine A
2A
receptor (A
2A
R) has been associated to D
2
R ago...

Alternative Titles

Full title

Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1926687498

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1926687498

Other Identifiers

ISSN

0893-7648

E-ISSN

1559-1182

DOI

10.1007/s12035-017-0696-y

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