Agonist-specific coupling of growth hormone secretagogue receptor type 1a to different intracellular...
Agonist-specific coupling of growth hormone secretagogue receptor type 1a to different intracellular signaling systems: Role of adenosine
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Basel: Karger
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Language
English
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Basel: Karger
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Contents
The growth hormone secretagogue receptor subtype 1a (GHSR-1a) is involved in biological actions of ghrelin by triggering intracellular second messengers coupled to heterotrimeric G-protein complex involving Galpha(q/11). Adenosine is a partial agonist of the GHSR-1a, binding to a binding pocket distinct from the one described for ghrelin. This sugg...
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Full title
Agonist-specific coupling of growth hormone secretagogue receptor type 1a to different intracellular signaling systems: Role of adenosine
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TN_cdi_proquest_miscellaneous_19267848
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_19267848
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ISSN
0028-3835
E-ISSN
1423-0194
DOI
10.1159/000076042
